Precision for Medicine, Oncology and Rare Disease is not your typical CRO. We are passionate about cultivating our culture and are proud to share extremely high CRA retention rates compared to industry averages.

CRAs join us, love their jobs, and stay because of the amazing people and enjoyable quality of life. You will focus on an average of one to two studies setting you up to be a protocol expert. Travel is reasonable and your work/life balance will benefit as a result. Most meaningfully - your voice will be heard. Working in a smaller CRO allows you to have influence and impact when it matters most and support from direct line management.

About you:

• You are calm, thoughtful, and responsive when things don’t go as planned.
• You are well-prepared, whether it be for an investigator meeting, site visit or project team update, always staying two steps ahead of the game.
• You find quick and creative ways of overcoming difficulties.
• You have an impeccable eye for detail.
• You identify potential study risks and propose solutions on how to mitigate them.
• You take responsibility in the quality and outcomes of your work.
• You are adept at handling conflict by using tried and true resolution strategies.

How we will keep you busy and support your growth:

You will monitor and own the progress of clinical studies at investigative sites and ensure that clinical studies are conducted, recorded, and reported per protocol, SOPs, ICH-GCP, and all applicable regulations and standards. You will coordinate all necessary activities required to set up and monitor a study (i.e., identify investigators; helping prepare regulatory submissions, conducting pre-study and initiation visits, etc.).

Senior CRAs handle appropriately sized clinical trials, and support Project Managers with trials that are larger in scope. You will also have the opportunity to train and mentor junior staff members. You will interact directly with clients, initiate payments, and participate in proposal activities, including development and client presentations.

Qualifications:

Minimum Required:

• 4-year college degree or equivalent experience

Other Required:

• CRA experience within the CRO or pharmaceutical industry; 2+ years for a CRA II and 3+ years for Senior CRAs
• Oncology experience
• Availability for domestic travel including overnight stays, which may constitute up to approximately 50-60% travel commitment (international travel may be required for some senior level positions)

Preferred:

• Graduate or postgraduate degree with a concentration in a scientific or healthcare discipline
• Two+ years of oncology experience
• Study start up activities experience
• For Senior CRAs, understanding of financial management

Precision for Medicine, Oncology & Rare Disease is a precision medicine CRO. Precision’s uniquely integrated offering enables the science of precision medicine by combining novel clinical trial designs, industry-leading operational and medical experts, advanced biomarker and data analytics solutions, and an unequivocal real passion for rare diseases and oncology.

Precision medicine is revolutionizing the attack on cancer—and we are passionate about helping you harness its power. We strike tumors on a molecular level using biomarkers to link specific mutations to specific treatments. We combine deep science with deep data from advanced technological platforms, then layer on specialized expertise in the design and execution of targeted, adaptive clinical trials. Ultimately, we deliver robust insights that inform real-time decisions—and optimize the oncology development pathway.

We invite you to learn more about our growing organization serving our clients that are researching groundbreaking cancer therapies. We strive to ensure employees feel appreciated for the contributions they make every single day. You will provide input and have your ideas valued and nurtured, impacting positive change for the company.

The Zonal group are one of the UK’s largest technology providers to the hospitality industry. Our products are used by over 11,000 pubs, restaurants, and hotels.  Customers include national brands like Pizza Express, JD Wetherspoons and All Bar One.
We provide our customers with the solutions they need to make their business a success.  These solutions include mobile apps for ordering and web apps for engaging with consumers either through loyalty or reservations. By linking these solutions to Zonal’s EPoS (till) system, we help hospitality brands to understand their customers’ behaviour and preferences, enabling them to excel in an increasingly competitive market.  

If you have booked a table or hotel room, ordered, and paid for food and drinks, received loyalty offers, or downloaded your favourite hang out’s app, you will likely have used a Zonal product. 

We are a family business with Scottish roots. We operate from our modern head office in Edinburgh to our Marketing Technologies Division in Staffordshire, or our Innovation Centre in Abingdon and hotel management solutions base in Cardiff.

What you’ll do

This role sits within the Zonal Managed Services team and is part of the wider Zonal Technical Services business unit. Our suite of SaaS, distributed systems and product integrations help our customers run their critical business operations and provide their customers in turn with industry leading hospitality technology products.  You’ll play a key role in the formation of a new area within Zonal: our Production Operations (ProdOps) team that aims to drive operational excellence and customer focus into the operation of our SaaS hosted application suite.

As a Senior Site Reliability Engineer, you’ll combine your software and systems engineering expertise in coding, system design, integration, deployment and ongoing maintenance to help build and run our industry leading SaaS solution. You will help build a new key Site Reliability Engineering (SRE) function within Zonal, implementing best practice monitoring, processes and tooling focussed on uptime, performance, and reduction of toil. You will work closely with engineering teams in Development and Platform Delivery (Networks, DBA, and Infrastructure) to uphold contracted Service Level Objectives (SLOs).  You will be tasked with ensuring our internal and externally available systems have reliability, and uptime appropriate to user’s needs.

The makeup of our systems is changing rapidly, and you’ll play a key part in helping us drive this forward.  We’re moving towards a modern DevOps landscape with technologies like Docker, IaC and microservices.  Initially we are working with our own hosted data centre infrastructure technology however, you’ll play a key role in our drive towards a future hybrid public-cloud position.

You will contribute towards driving an organisational change into Zonal focussing on the core tenants of Site Reliability Engineering, namely the availability, latency, performance, efficiency, change management, monitoring, emergency response, and capacity planning of our SaaS service(s).

You and your team will:

• Build strong, collaborative relationships acting as the glue between in-house customer facing support and delivery teams, product management, and platform engineering (R&D) teams
• Create frameworks to continually improve:
  • Observability through logging, monitoring, and alerting
  • Capacity analytics and demand management
  • Dashboards, internal and external status pages
  • CI / CD pipelines, release processes
  • Automation of manual processes, tooling and IaC including security checks and break-glass procedures
  • Ownership of some cross-cutting implementation like logs / metrics infrastructure
  • Team processes, driving technical debt down
  • Triage, response, and recovery times
  • Disaster Recovery models and planning
• Reduce toil (work that is largely manual, repetitive, automatable, tactical, devoid of enduring value, and that scales linearly as our services grow), maximising engineering capacity 
• Bring expertise and a streetwise perspective to problem solving, reduction of complexity and reliability patterns
• Participate in On-Call cover and Incident Response
• Play a key role in change management and delivery pipeline into production ensuring safety, predictability, repeatability, and auditability of all build and deploy processes
• Proactively manage delivery of key SLOs covering Detection / early warning and self-healing
• Own all monitoring and alerting applications, services and infrastructure
• Act as key stakeholders in the technical debt reduction of our Products by contributing towards the Tech Debt backlogs for our R&D teams

Who you are

You will have a background in deploying, managing, and operating mission critical distributed SaaS systems having spent at least some of your career as a member of a fast-paced product engineering, web operations and/or platform delivery team.  Ideally you will have a demonstrable track record of operating systems in hybrid datacentre/cloud infrastructures.

When things go wrong – and they will – we want to know about the problem before our users, so will need your deep understanding of modern monitoring and toolsets for identification, investigation, and remediation.

• A self-starter with a passion for technology and problem solving, with excellent analytical skills who thrives in a fast-paced autonomous environment leading from the front
• A champion of resilience, consistency, security, and monitoring 
• Solid experience in scripting, tooling, automation, and Infrastructure as Code (IaC) frameworks
• In-depth knowledge and experience of monitoring frameworks such as Zabbix/GreyLog
• Excellent understanding of traditional ops areas of expertise: Windows/Linux, Networking etc.
• Good familiarity with docker and container ecosystem including technologies such as Kubernetes
• Quick to spot opportunities and new capabilities in technologies
• Familiar with database technologies such as MySQL and MSSQL
• Comfortable in complex provisioning and deployment scenarios, modern CI/CD pipelines
• A strong collaborator, organised, and has a safe pair of hands
• A team player that enjoys influencing change, leading and developing a technical function
• Comfortable communicating to mixed audiences of Support, Product Delivery, Engineering, and Incident Management
• Critical thinking skills, a delivery-oriented attitude, and attention to detail.
• Minimum 5 years’ experience building, deploying and maintaining production software.

What we value

Passion, Teamwork, Innovation and Professionalism are the values we believe make us the company we are. We are looking for someone who understands great culture and will help us shape it as it evolves.

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Precision for Medicine is a precision medicine CRO. Our uniquely integrated offering enables the science of precision medicine by combining novel clinical trial designs, industry-leading operational and medical authorities, advanced biomarker and data analytics solutions, and an unequivocal real passion for rare diseases and oncology.

We offer opportunities for both CTAs and Senior CTAs who will be providing administrative support to project teams in clinical operations. You will support several clinical programs and participate on a number of project teams as a valued member of the Project Team contributing towards efficient management of trials. Senior level CTAs serve as Subject Matter Experts with a focus on mentoring and training.

About You:

• You are calm, thoughtful, and responsive when things don’t go as planned.
• You are well-prepared, whether it be for an investigator meeting, site visit or project team update, always staying two steps ahead of the game.
• You find quick and creative ways of overcoming difficulties.
• You have an impeccable eye for detail.
• You identify potential study risks and know how to mitigate them.
• You are adept at handling conflict by using tried and true resolution strategies.
• You are ambitious, collaborative, agile, and a standout colleague.

How we will keep you busy and support your growth:

• Handling inventory, tracking, and shipping for clinical trials supplies (consisting of CRFs, study drug where applicable, and other supplies)
• Assisting with preparation and shipment of Operating Manuals
• Developing and maintaining the study specific investigator database for use with correspondence and mail merges
• Updating and maintaining study tracking including a master team contact list
• Preparing and distributing initial site start up packages and liaises with the sites to obtain required regulatory documents
• Assisting team leaders in the production of study reports and updates
• Serving as an office based point of contact for all sites during the course of the study as well as provides phone coverage for travelling team members
• Preparing investigator budget payments and distributing to sites
• Serving as administrator of the Trial Master File with direction from Project Management, including the preparation, maintenance, and archiving of the TMF
• Identifying and processing Serious Adverse Events according to the procedures defined by the study team
• Assisting with study start-up of clinical trials, including feasibility, investigator recruitment, collection of regulatory documents and general site management support

Qualifications:

Minimum Required:

• UK GCSE or equivalent local level qualifications

Other Required:

• Experience in a Clinical Trial Administration role or related discipline; CTAs will have 1-3 years and Sr. CTAs will have 3-5 years of experience
• Basic computer skills, including word processing
• Working knowledge of ICH-GCP, SOPs, and regulatory guidance including a good knowledge of the regulatory and safety processes
• Limited travel may be required for this position

Preferred:

• CRO experience

About Precision for Medicine

Precision medicine is revolutionizing the attack on cancer—and we are passionate about helping our clients harness its power. We strike tumors on a molecular level using biomarkers to link specific mutations to specific treatments. We combine deep science with deep data from advanced technological platforms, then layer on specialized expertise in the design and execution of targeted, adaptive clinical trials. Ultimately, we deliver robust insights that inform real-time decisions—and optimize the oncology development pathway.